2,3-二(2-噻吩基)喹喔啉合成路线 （共 7 条）
反应条件
1: With N,N,N',N,-tetramethylethylenediamine in toluene
T=50°C; 10 h; Inert atmosphere;
2: With water; ammonium chloride in toluene
12 h;
参考文献
Zhuo, Fang-Fang; Xie, Wen-Wen; Yang, Yong-Xin; Zhang, Lei; Wang, Pei; Yuan, Rui; Da, Chao-Shan
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3243 - 3249
反应条件
potassium permanganate in acetone
T=35 - 40°C;
参考文献
Kauffmann, Thomas; Ghanem, Mohammad; Otter, Rolf
Chemische Berichte, 1982 , vol. 115, # 2 p. 459 - 466
反应条件
air in tetrahydrofuran; ethyl acetate
T=20°C;
参考文献
Hu, Zhong-Yuan; Du, Ding; Tang, Wei-Fang; Lu, Tao
Asian Journal of Chemistry, 2012 , vol. 24, # 5 p. 2262 - 2264
反应条件
1: 1) 2M BuLi / 1) THF, ether, hexane, 1,5 h, 0-10 deg C, 2) THF, ether, hexane, -70 deg C, 22 h
2: 62 percent / KMnO4 / acetone / 35 - 40 °C
View Scheme
参考文献
Kauffmann, Thomas; Ghanem, Mohammad; Otter, Rolf
Chemische Berichte, 1982 , vol. 115, # 2 p. 459 - 466
反应条件
1: 2,5,6,7-tetrahydro-2-phenyl-3H-pyrrolo[2,1-c]-1,2,4-triazol-3-ylidenium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 3 h / 65 °C / Inert atmosphere
2: air / tetrahydrofuran; ethyl acetate / 20 °C
View Scheme
参考文献
Hu, Zhong-Yuan; Du, Ding; Tang, Wei-Fang; Lu, Tao
Asian Journal of Chemistry, 2012 , vol. 24, # 5 p. 2262 - 2264
参考文献
Deschamps et al.
Journal of Organic Chemistry, 1949 , vol. 14, p. 184,186
反应条件
T=350°C; Yield given. Yields of byproduct given;
参考文献
Ochoa, Carmen; Rodriguez, Juan
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 1053 - 1055
