3-溴-4-甲氧基苯甲酰氯合成路线 （共 3 条）
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane; toluene
4 h;
参考文献
ASTRAZENECA AB
Patent: US2010/125081 A1, 2010 ;
Location in patent: Page/Page column 30 ;
US 20100125081 A1
反应条件
1: bromine / tetrachloromethane / 24 h / 40 - 45 °C
2: thionyl chloride; N,N-dimethyl-formamide / 3 h / 80 - 90 °C
View Scheme
参考文献
Zheng, Fei Lang; Ban, Shu Rong; Feng, Xiu E; Zhao, Cheng Xiao; Lin, Wenhan; Li, Qing Shan
Molecules, 2011 , vol. 16, # 6 p. 4897 - 4911
反应条件
1: 77 percent / KOH / methanol; H2O / 4 h / Heating
2: thionyl chloride / 1 h / Heating
View Scheme
参考文献
Laatsch, Hartmut; Pudleiner, Heinz
Liebigs Annalen der Chemie, 1989 , p. 863 - 882
