1: 97 percent / 40percent aq. methylamine / aq. ethanol / 2 h / Ambient temperature 2: 72 percent / 7 h / Ambient temperature View Scheme

1: 39 percent / triphenylphosphine, palladium chloride, cuprous iodide, diethylamine / CH2Cl2 / 20 h / Ambient temperature 2: 97 percent / 40percent aq. methylamine / aq. ethanol / 2 h / Ambient temperature 3: 72 percent / 7 h / Ambient temperature View Scheme

1: 1.) sodium nitrite, conc. sulfuric acid, 2.) aq. potassium iodide / 1.) 1 h, 2.) room temp., overnight 2: 39 percent / triphenylphosphine, palladium chloride, cuprous iodide, diethylamine / CH2Cl2 / 20 h / Ambient temperature 3: 97 percent / 40percent aq. methylamine / aq. ethanol / 2 h / Ambient temperature 4: 72 percent / 7 h / Ambient temperature View Scheme

7 h; Ambient temperature;