四氢呋喃-2-甲酸 (3-甲基氨基丙基)酰胺合成路线 （共 7 条）
反应条件
ammonia; hydrogen; Rh on carbon T=80°C; P=43440.4 Torr;
参考文献
Manoury; Binet; Dumas; Lefevre-Borg; Cavero
Journal of Medicinal Chemistry, 1986 , vol. 29, # 1 p. 19 - 25
参考文献
Chou, Wen-Chih; Tan, Chang-Wei; Chen, Shyh-Fong; Ku, Hao
Journal of Organic Chemistry, 1998 , vol. 63, # 26 p. 10015 - 10017
反应条件
1,1,1,3,3,3-hexamethyl-disilazane T=110°C; 8 h;
参考文献
Chou, Wen-Chih; Chou, Ming-Chen; Lu, Yann-Yu; Chen, Shyh-Fong
Tetrahedron Letters, 1999 , vol. 40, # 17 p. 3419 - 3422
反应条件
1: Et3N / tetrahydrofuran / 0.25 h / 5 °C 2: tetrahydrofuran / Ambient temperature 3: 68 percent / H2, 10percent ethanolic NH3 / Rh/C / 80 °C / 43440.4 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 1 p. 19 - 25
反应条件
1: tetrahydrofuran / Ambient temperature 2: 68 percent / H2, 10percent ethanolic NH3 / Rh/C / 80 °C / 43440.4 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 1 p. 19 - 25
反应条件
in 3-methyl-1-butanol 12 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 1 p. 19 - 25
反应条件
in 3-methyl-1-butanol T=25 - 128°C; 12 h; Heating / reflux;
参考文献
UNICHEM LABORATORIES LIMITED
Patent: WO2008/84493 A2, 2008 ;
Location in patent: Page/Page column 9 ;
