4-(4,5-二氢-2-噁唑)苯酚合成路线 （共 10 条）
反应条件
thionyl chloride; sodium hydrogencarbonate
参考文献
Langer, Vratislav; Koos, Miroslav; Gyepesova, Dalma; Sladkovicova, Mariana; Luston, Jozef; Kronek, Juraj
Acta Crystallographica Section C: Crystal Structure Communications, 2005 , vol. 61, # 10 p. o602-o606
反应条件
5-palladium/activated carbon; hydrogen in ethanol
T=20°C; 1.5 h;
参考文献
Minkkilae, Anna; Myllymaeki, Mikko J.; Saario, Susanna M.; Castillo-Melendez, Joel A.; Koskinen, Ari M.P.; Fowler, Christopher J.; Leppaenen, Jukka; Nevalainen, Tapio
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 7 p. 2994 - 3008
反应条件
potassium carbonate in water
T=90°C; 6 h;
参考文献
Goud, D. Raghavender; Pathak, Uma
Synthesis (Germany), 2012 , vol. 44, # 23 art. no. SS-2012-Z0598-OP, p. 3678 - 3682
反应条件
indium(III) chloride; 1-n-butyl-3-methylimidazolium chloride
T=60°C; 3 h;
参考文献
Kamakshi; Reddy, Boreddy S.R.
Australian Journal of Chemistry, 2006 , vol. 59, # 7 p. 463 - 467
反应条件
sulfuric acid; benzene
参考文献
Boyer; Hamer
Journal of the American Chemical Society, 1955 , vol. 77, p. 951,953
反应条件
in methanol
T=40°C; 48 h;
参考文献
Nonnenmacher, Alex; Plieninger, Hans
Chemische Berichte, 1982 , vol. 115, # 3 p. 1244 - 1246
反应条件
1: HCl / diethyl ether / 24 h / -4 °C
2: 15 percent / methanol / 48 h / 40 °C
View Scheme
参考文献
Nonnenmacher, Alex; Plieninger, Hans
Chemische Berichte, 1982 , vol. 115, # 3 p. 1244 - 1246
反应条件
1: 139.85 °C
2: thionyl chloride; NaHCO3
View Scheme
参考文献
Langer, Vratislav; Koos, Miroslav; Gyepesova, Dalma; Sladkovicova, Mariana; Luston, Jozef; Kronek, Juraj
Acta Crystallographica Section C: Crystal Structure Communications, 2005 , vol. 61, # 10 p. o602-o606
反应条件
potassium carbonate; sodium iodide in acetonitrile
24 h; Heating;
参考文献
Diana, Guy D.; Oglesby, Richard C.; Akullian, Vahan; Carabateas, Phillip M.; Cutcliffe, David; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 383 - 388
反应条件
potassium carbonate; sodium iodide in acetonitrile
24 h; Heating;
参考文献
Diana, Guy D.; Oglesby, Richard C.; Akullian, Vahan; Carabateas, Phillip M.; Cutcliffe, David; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 383 - 388
