3-乙酰-1-(苯磺酰基)吡咯合成路线 （共 18 条）
反应条件
sodium hydroxide in 1,4-dioxane 15 h; Ambient temperature;
参考文献
Cadamuro, Silvano; Degani, Iacopo; Dughera, Stefano; Fochi, Rita; Gatti, Antonella; Piscopo, Laura
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 2 p. 273 - 284
反应条件
water; bromine in 1,4-dioxane 5 h;
参考文献
Kamogawa, Hiroyoshi; Nakata, Takuharu; Ohori, Shin; Komatsu, Sei
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 3 p. 1066 - 1068
反应条件
1: aq. sodium hypobromite / dioxane / 2 h
2: H2SO4 / Heating
3: DIBAL-H / CHCl3; toluene / 3 h / Ambient temperature
4: MnO2 / toluene; CHCl3 / 4 h / Heating
View Scheme
参考文献
Fuji; Muratake; Natsume
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 9 p. 2338 - 2343
反应条件
1: With trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine in dichloromethane
T=0 - 20°C; 2 h; Molecular sieve;
2: With Palau′chlor in dichloromethane
T=20°C; 2 h; Molecular sieve; chemoselective reaction;
参考文献
Rodriguez, Rodrigo A.; Pan, Chung-Mao; Yabe, Yuki; Kawamata, Yu; Eastgate, Martin D.; Baran, Phil S.
Journal of the American Chemical Society, 2014 , vol. 136, # 19 p. 6908 - 6911
反应条件
aluminium trichloride; tBuNH2·BH3 in dichloromethane
T=25°C; 3 h;
参考文献
Ketcha, Daniel M.; Carpenter, Kenneth P.; Atkinson, Steven T.; Rajagopalan, Hema R.
Synthetic Communications, 1990 , vol. 20, # 11 p. 1647 - 1655
反应条件
1: 51 percent / KOH, N2H4.H2O / various solvent(s) / 5.5 h / Heating
2: 29 percent / potassium metal / tetrahydrofuran / Ambient temperature
3: 5 percent / AlCl3 / CH2Cl2 / 42 h / Ambient temperature; further catalyst SnCl4
4: KOH / methanol / hydrolysis
View Scheme
参考文献
Anderson, Hugh J.; Loader, Charles E.; Xu, Ru Xun; Le, Nghia; Gogan, Niall J.; et al.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 896 - 902
反应条件
1: 51 percent / KOH, N2H4.H2O / various solvent(s) / 5.5 h / Heating
2: 29 percent / potassium metal / tetrahydrofuran / Ambient temperature
3: 32 percent Spectr. / AlCl3 / CH2Cl2 / 42 h / Ambient temperature; further catalyst SnCl4
4: KOH / methanol / hydrolysis
View Scheme
参考文献
Anderson, Hugh J.; Loader, Charles E.; Xu, Ru Xun; Le, Nghia; Gogan, Niall J.; et al.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 896 - 902
反应条件
1: 100 percent / aq. 17percent NaOH / dioxane / 15 h / Ambient temperature
2: 92 percent / anhydrous AlCl3 / CH2Cl2 / 0.5 h / Ambient temperature
View Scheme
参考文献
Cadamuro, Silvano; Degani, Iacopo; Dughera, Stefano; Fochi, Rita; Gatti, Antonella; Piscopo, Laura
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 2 p. 273 - 284
