2,2,4,4-四甲基-3-戊酮合成路线 （共 175 条）
反应条件
in diethyl ether
T=20°C; 0.5 h;
参考文献
Shen, Kao-Hsien; Yao, Ching-Fa
Journal of Organic Chemistry, 2006 , vol. 71, # 10 p. 3980 - 3983
参考文献
Hopf, Henning; Haenel, Ralf; Jones, Peter G.; Bubenitschek, Peter
Angewandte Chemie, 1994 , vol. 106, # 13 p. 1444 - 1445
反应条件
(i) pentane, (ii) H2NCH2CH2OH; Multistep reaction;
参考文献
Kramer,G.W.; Brown,H.C.
Journal of Organic Chemistry, 1977 , vol. 42, p. 2292 - 2299
参考文献
Kurischko; Lipatnikow
Naucn.Zap.Uzgorodsk.Univ.Chem.Abstr., 1957 , vol. 22, p. 113,115
Naucn.Zap.Uzgorodsk.Univ.Chem.Abstr., 1960 , p. 7530
Show Details
Andrac
Annales de Chimie (Cachan, France), 1964 , vol. <13>9, p. 287,298
Show Details
Sokolowa; Fedorina
Trudy Moskovsk.chim.technol.Inst.Chem.Abstr., 1956 , # 23 p. 35,38
Trudy Moskovsk.chim.technol.Inst.Chem.Abstr., 1959 , p. 9029
反应条件
1: 91 percent / diethyl ether / 1 h / Heating
2: 91 percent / SOCl2 / pyridine / 0 - 5 °C
3: 76 percent / H2O2, 3N NaOH / tetrahydrofuran
View Scheme
参考文献
Newman,M.S. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 2498 - 2501
参考文献
Adcock, James L.; Robin, Mark L.
Journal of Organic Chemistry, 1984 , vol. 49, # 8 p. 1442 - 1445
参考文献
Dubois, Jacques-Emile; Zhang, Ben Li; Lion, Claude
Tetrahedron, 1981 , vol. 37, # 24 p. 4189 - 4194
反应条件
diethyl ether; sodium
参考文献
Bartlett; Schneider
Journal of the American Chemical Society, 1945 , vol. 67, p. 143
参考文献
Helaja, T. Tuulamari; Loefgren, Barbro; Hase, Tapio
Acta Chemica Scandinavica, 1999 , vol. 53, # 5 p. 352 - 355
反应条件
in diethyl ether
T=25°C; 1 h; effects of salts (MeOK, t-BuOLi), other reaction time: 24 h; Product distribution;
参考文献
Richey, Herman G.; DeStephano, Joseph P.
Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3281 - 3286
