[3S-(1Z,3a,5b)]-[2-[3,5-二[(叔丁基)二甲基硅氧基]-2-亚甲基环己亚基]乙基]二苯基氧化膦合成路线 （共 36 条）
反应条件
dihydrogen peroxide 1.) THF, -70 deg C, 2.) CH2Cl2, 1 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 51, # 16 p. 3098 - 3108
反应条件
1: tetrahydrofuran / 1 h / -78 °C 2: (Bu)4NF / tetrahydrofuran / 25 °C View Scheme
参考文献
Baggiolini, Enrico G.; Iacobelli, Jerome A.; Hennessy, Bernard M.; Uskokovic, Milan R.
Journal of the American Chemical Society, 1982 , vol. 104, # 10 p. 2945 - 2948
反应条件
n-butyllithium 1.) THF, n-hexane, -78 deg C, 5 min, 2.) THF, n-hexane, -78 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Baggiolini, Enrico G.; Iacobelli, Jerome A.; Hennessy, Bernard M.; Batcho, Andrew D.; Sereno, John F.; Uskokovic, Milan R.
Journal of Organic Chemistry, 1986 , vol. 51, # 16 p. 3098 - 3108
反应条件
1.1: 93 percent / nBuLi / tetrahydrofuran; hexane / -78 - -40 °C 2.1: tetrahydrofuran / 1 h / -78 °C 2.2: 77 percent / NBu4F / tetrahydrofuran / 20 °C View Scheme
参考文献
Fall, Yagamare; Gonzalez, Victoria; Vidal, Beatriz; Mourino, Antonio
Tetrahedron Letters, 2002 , vol. 43, # 3 p. 427 - 429
反应条件
n-butyllithium 1.) THF, n-hexane, -78 deg C, 5 min, 2.) THF, n-hexane, -78 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Baggiolini, Enrico G.; Iacobelli, Jerome A.; Hennessy, Bernard M.; Batcho, Andrew D.; Sereno, John F.; Uskokovic, Milan R.
Journal of Organic Chemistry, 1986 , vol. 51, # 16 p. 3098 - 3108
反应条件
1.1: n-hexyl lithium / -78 °C 2.1: bis(cyclohexanyl)borane; diethylzinc; (+)-DAIB / hexane / -20 - 0 °C 2.2: 0 °C 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C View Scheme
参考文献
Rumbo, Antonio; Perez-Garcia, Xenxo; Mourino, Antonio
Journal of Steroid Biochemistry and Molecular Biology, 2010 , vol. 121, # 1-2 p. 68 - 70
