Prothracarcin合成路线 （共 16 条）
反应条件
1: 1.) t-BuOK / 1.) THF, 20 min; 2.) THF, room temperature, 1 h
2: 30 percent / MCPBA, NaHCO3 / not given
3: 1.) Li, ClPPh2 / 1.) THF; 2.) THF
4: 1.) NaBH4; 2.) silica gel / 1.) EtOH, 0 degC, 3 h; 2.) room temperature, 30 min, benzene
View Scheme
参考文献
Mori, Miwako; Uozumi, Yasuhiro; Kimura, Masaya; Ban, Yoshio
Tetrahedron, 1986 , vol. 42, # 14 p. 3793 - 3806
反应条件
1: 30 percent / MCPBA, NaHCO3 / not given
2: 1.) Li, ClPPh2 / 1.) THF; 2.) THF
3: 1.) NaBH4; 2.) silica gel / 1.) EtOH, 0 degC, 3 h; 2.) room temperature, 30 min, benzene
View Scheme
参考文献
Mori, Miwako; Uozumi, Yasuhiro; Kimura, Masaya; Ban, Yoshio
Tetrahedron, 1986 , vol. 42, # 14 p. 3793 - 3806
反应条件
1: P2I4 / CH2Cl2; pyridine / 16 h / 30 °C
2: 1.) NaBH4; 2.) silica gel / 1.) EtOH, 0 degC, 3 h; 2.) room temperature, 30 min, benzene
View Scheme
参考文献
Mori, Miwako; Uozumi, Yasuhiro; Kimura, Masaya; Ban, Yoshio
Tetrahedron, 1986 , vol. 42, # 14 p. 3793 - 3806
反应条件
1: Et3N / CH2Cl2 / 0.08 h / 0 °C
2: KOH / methanol / 0.03 h / 0 °C
3: P2I4 / CH2Cl2; pyridine / 16 h / 30 °C
4: 1.) NaBH4; 2.) silica gel / 1.) EtOH, 0 degC, 3 h; 2.) room temperature, 30 min, benzene
View Scheme
参考文献
Mori, Miwako; Uozumi, Yasuhiro; Kimura, Masaya; Ban, Yoshio
Tetrahedron, 1986 , vol. 42, # 14 p. 3793 - 3806
反应条件
1: KOH / methanol / 0.03 h / 0 °C
2: P2I4 / CH2Cl2; pyridine / 16 h / 30 °C
3: 1.) NaBH4; 2.) silica gel / 1.) EtOH, 0 degC, 3 h; 2.) room temperature, 30 min, benzene
View Scheme
参考文献
Mori, Miwako; Uozumi, Yasuhiro; Kimura, Masaya; Ban, Yoshio
Tetrahedron, 1986 , vol. 42, # 14 p. 3793 - 3806
反应条件
sodium tetrahydroborate; silica gel
1.) EtOH, 0 degC, 3 h; 2.) room temperature, 30 min, benzene; Yield given. Multistep reaction;
参考文献
Mori, Miwako; Uozumi, Yasuhiro; Kimura, Masaya; Ban, Yoshio
Tetrahedron, 1986 , vol. 42, # 14 p. 3793 - 3806
