乙基2-溴-4-(2-甲基-2-丙基)-1,3-噻唑-5-羧酸酯合成路线 （共 3 条）
反应条件
sulfuric acid; copper(II) sulfate; sodium bromide; sodium nitrite in water
T=-8 - 8°C; 1 h;
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
反应条件
1: 25.6 g / Br2 / H2O / 0.5 h / 0 °C
2: 22 g / ethanol / 1 h / Heating
3: 9.1 g / NaBr, CuSO4, H2SO4, NaNO2 / H2O / 1 h / -8 - 8 °C
View Scheme
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
反应条件
1: 22 g / ethanol / 1 h / Heating
2: 9.1 g / NaBr, CuSO4, H2SO4, NaNO2 / H2O / 1 h / -8 - 8 °C
View Scheme
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
