4-甲基噻唑-5-甲酸甲酯合成路线 (共 9 条)
反应条件
1: ethanolic NaOH 2: diethyl ether View Scheme
参考文献
Journal of the American Chemical Society, , vol. 57, p. 1879
反应条件
1: sulfuryl chloride 2: ethanol View Scheme
参考文献
Journal of Medicinal and Pharmaceutical Chemistry, , vol. 1, p. 577,594
Journal of the American Chemical Society, , vol. 61, p. 891
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 228, p. 27,31
Journal of the American Chemical Society, , vol. 57, p. 1879
参考文献
Journal of Medicinal and Pharmaceutical Chemistry, , vol. 1, p. 577,594
Journal of the American Chemical Society, , vol. 61, p. 891
参考文献
WO2012/30990 A1, ;
Page/Page column 79-80 ;
WO 2012/030990 A1
参考文献
Journal of the Chemical Society, , p. 1030
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=5 - 15°C; 2.5 - 3.5 h; 2: With sodium sulfate in tetrahydrofuran; water
参考文献
Orchid Chemicals and Pharmaceuticals Limited
Patent: US2003/204095 A1, 2003 ;
Location in patent: Page/Page column 2 ;
反应条件
1: ethanol; N2H4+H2O 2: pyridine 3: Na2CO3; ethylene glycol View Scheme
参考文献
Campaigne et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1959 , vol. 1, p. 577,594
Full Text Show Details
Buchman; Richardson
Journal of the American Chemical Society, 1939 , vol. 61, p. 891
反应条件
ethanol; hydrazine hydrate
参考文献
Campaigne et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1959 , vol. 1, p. 577,594
Full Text Show Details
Buchman; Richardson
Journal of the American Chemical Society, 1939 , vol. 61, p. 891
Full Text View citing articles Show Details
Takata et al.
Yakugaku Zasshi, 1953 , vol. 73, p. 126
Chem.Abstr., 1953 , p. 12358