乙基2-溴-4-丙基-1,3-噻唑-5-羧酸酯合成路线 （共 5 条）
反应条件
sulfuric acid; copper(II) sulfate; sodium bromide; sodium nitrite in water
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
反应条件
1: ethanol
2: NaBr, CuSO4, H2SO4, NaNO2 / H2O
View Scheme
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
反应条件
1: sulfuryl dichloride / dichloromethane / 0.01 h / 25 °C / |Inert atmosphere
2: acetonitrile / 0.2 h / 80 °C
3: isopentyl nitrite; copper(I) bromide / acetonitrile / 0.2 h / 0.25 - 65 °C
View Scheme
参考文献
Sharma, Lalima; Sattigeri, Jitendra A.; Kumar, Narest; Yadav, Ajay; Momim, Rijwan; Ahmed, Shahadat; Cliffe, Ian A.; Bhatnagar, Pradip Kumar; Ghosh, Sanjay; Raj, V. Samuel; Upadhyay, Dilip J.
Patent: US2012/108565 A1, 2012 ;
反应条件
1: acetonitrile / 0.2 h / 80 °C
2: isopentyl nitrite; copper(I) bromide / acetonitrile / 0.2 h / 0.25 - 65 °C
View Scheme
参考文献
Sharma, Lalima; Sattigeri, Jitendra A.; Kumar, Narest; Yadav, Ajay; Momim, Rijwan; Ahmed, Shahadat; Cliffe, Ian A.; Bhatnagar, Pradip Kumar; Ghosh, Sanjay; Raj, V. Samuel; Upadhyay, Dilip J.
Patent: US2012/108565 A1, 2012 ;
反应条件
potassium hydroxide in water
Heating;
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
