乙基2-溴-4-异丙基-1,3-噻唑-5-羧酸酯合成路线 （共 2 条）
反应条件
copper(I) bromide; isopentyl nitrite in acetonitrile
T=80°C; 3 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2007/92751 A2, 2007 ;
Location in patent: Page/Page column 18-19 ;
反应条件
1: ethanol
2: NaBr, CuSO4, H2SO4, NaNO2 / H2O
View Scheme
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
