2-(4-甲基-5-异恶唑基胺)-N-(4-甲基-5-异恶唑基)-1,4-萘醌-4-亚胺合成路线 (共 3 条)
反应条件
sodium hydroxide in ethanol T=70°C;
参考文献
Longhi; De Bertorello; Brinon
Journal of Pharmaceutical Sciences, 1991 , vol. 80, # 6 p. 573 - 577
反应条件
hydrogenchloride
Substitution; condensation; 0.166667 h; Heating;
参考文献
Ortiz, C. S.; Longhi, M. R.; Bertorello, M. M. de; Brinon, M. C.
Organic Preparations and Procedures International, 1991 , vol. 23, # 2 p. 181 - 185
反应条件
water in ethanol
T=70°C; μ=0.5, var. acidic and neutral pH, var. temp.; mechanism, Ea; Rate constantKineticsThermodynamic data;
参考文献
Longhi; De Bertorello; Brinon
Journal of Pharmaceutical Sciences, 1991 , vol. 80, # 6 p. 573 - 577