3-(1,3-二氧戊环-2-基)丙酸甲酯合成路线 （共 4 条）
反应条件
1: 2-(1,3-dioxa-2-cyclopentyl)-ethyl bromide With iodine; magnesium; ethylene dibromide in tetrahydrofuran
1 h;
2: methyl chloroformate in tetrahydrofuran
T=-78 - 20°C;
参考文献
Liu, Xuan; West
Chemical Communications, 2006 , # 48 p. 5036 - 5038
反应条件
hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal
Multistep reaction;
参考文献
Parry; Naidu
Journal of the American Chemical Society, 1982 , vol. 104, # 11 p. 3217 - 3219
反应条件
T=30°C; 6 h; Irradiation;
参考文献
Arbuzov, P. V.; Voronkov, M. G.; Mirskov, R. G.; Stankevich, V. K.; Kukharev, B. F.; et al.
Russian Chemical Bulletin, 1995 , vol. 44, # 9 p. 1755 - 1757
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 1995 , # 9 p. 1824 - 1826
反应条件
1: methanephosphonic acid dimethyl ester With n-butyllithium in tetrahydrofuran
T=-78°C; 1 h;
2: 3-[1,3]Dioxolan-2-yl-propionic acid methyl ester in tetrahydrofuran
T=-78°C; 3 h;
参考文献
Liu, Xuan; West
Chemical Communications, 2006 , # 48 p. 5036 - 5038
