2-羟基-5-(甲氧基甲氧基)-3,4-二甲基苯甲酸合成路线 （共 4 条）
反应条件
potassium hydroxide in methanol
T=50°C; 2.5 h;
参考文献
Mazzini, Francesco; Netscher, Thomas; Salvadori, Piero
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9303 - 9306
反应条件
1: 91 percent / MgBr2 / benzene / 20 °C
2: 100 percent / KOH / methanol / 2.5 h / 50 °C
View Scheme
参考文献
Mazzini, Francesco; Netscher, Thomas; Salvadori, Piero
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9303 - 9306
反应条件
1.1: 93 percent / NaH / dimethylformamide / 0 - 20 °C
2.1: t-BuLi / hexane; pentane / 3 h / 0 °C
2.2: 84 percent / hexane; pentane / 3 h / 0 °C
3.1: 91 percent / MgBr2 / benzene / 20 °C
4.1: 100 percent / KOH / methanol / 2.5 h / 50 °C
View Scheme
参考文献
Mazzini, Francesco; Netscher, Thomas; Salvadori, Piero
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9303 - 9306
反应条件
1.1: t-BuLi / hexane; pentane / 3 h / 0 °C
1.2: 84 percent / hexane; pentane / 3 h / 0 °C
2.1: 91 percent / MgBr2 / benzene / 20 °C
3.1: 100 percent / KOH / methanol / 2.5 h / 50 °C
View Scheme
参考文献
Mazzini, Francesco; Netscher, Thomas; Salvadori, Piero
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9303 - 9306
