1: H2O/KOH / ethanol / 16 h / Ambient temperature 2: hydrazine hydrate, KOH / bis-(2-hydroxy-ethyl) ether / 10 h / Heating 3: 91 percent / concn H2SO4 / 1,2-dichloro-ethane / 20 h / Heating 4: 92 percent / BF3*OEt2 / Ambient temperature 5: 94 percent / NaOMe / methanol / 2 h / Heating 6: 92 percent / SF4 / 24 h / Ambient temperature 7: 96 percent / H2O/KOH / ethanol / 16 h / Ambient temperature 8: 90 percent / diethyl ether; hexane / 2 h / Heating 9: 77 percent / m-chloroperbenzoic acid / CH2Cl2 / 72 h / Ambient temperature 10: 93 percent / NaOMe / methanol / 2 h / Heating 11: 81 percent / SF4 / 24 h / Ambient temperature View Scheme

1: H2O/KOH / ethanol / 16 h / Ambient temperature 2: hydrazine hydrate, KOH / bis-(2-hydroxy-ethyl) ether / 10 h / Heating 3: 91 percent / concn H2SO4 / 1,2-dichloro-ethane / 20 h / Heating 4: 92 percent / BF3*OEt2 / Ambient temperature 5: 94 percent / NaOMe / methanol / 2 h / Heating View Scheme

1: H2O/KOH / ethanol / 16 h / Ambient temperature 2: hydrazine hydrate, KOH / bis-(2-hydroxy-ethyl) ether / 10 h / Heating View Scheme

1: H2O/KOH / ethanol / 16 h / Ambient temperature 2: hydrazine hydrate, KOH / bis-(2-hydroxy-ethyl) ether / 10 h / Heating 3: 91 percent / concn H2SO4 / 1,2-dichloro-ethane / 20 h / Heating 4: 92 percent / BF3*OEt2 / Ambient temperature 5: 94 percent / NaOMe / methanol / 2 h / Heating 6: 92 percent / SF4 / 24 h / Ambient temperature 7: 96 percent / H2O/KOH / ethanol / 16 h / Ambient temperature 8: thionyl chloride View Scheme