1H-吡咯-2,3,5-三甲醛合成路线 （共 6 条）
反应条件
tetrafluoroboric acid; mercury(II) oxide in dimethyl sulfoxide
T=60°C; 4 h;
参考文献
Cadamuro, Silvano; Degani, Iacopo; Fochi, Rita; Gatti, Antonella; Piscopo, Laura
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 19 p. 2365 - 2369
反应条件
toluene-4-sulfonic acid in ethanol; water
1.) reflux 1 h, 2.) heating 3.3 h;
参考文献
Loader, Charles E.; Barnett, Graham H.; Anderson, Hugh J.
Canadian Journal of Chemistry, 1982 , vol. 60, p. 383 - 389
反应条件
1: 1.) POCl3 / 1.) r.t., 15 min, 2.) 4 h
2: 60 percent / 35percent aq. HBF4, HgO / dimethylsulfoxide / 60 °C
View Scheme
参考文献
Cadamuro, Silvano; Degani, Iacopo; Fochi, Rita; Gatti, Antonella; Piscopo, Laura
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 19 p. 2365 - 2369
反应条件
1: 90 percent / glacial AcOH / 2 h / 70 °C
2: 60 percent / HgO, aq. HBF4 / dimethylsulfoxide / 4 h / 60 °C
View Scheme
参考文献
Cadamuro, Silvano; Degani, Iacopo; Fochi, Rita; Gatti, Antonella; Piscopo, Laura
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 23 p. 2939 - 2944
反应条件
1: 68 percent
2: 77 percent / phosphorus oxychloride / 1.83 h / 0 °C
3: 67 percent / p-toluenesulfonic acid / H2O; ethanol / 1.) reflux 1 h, 2.) heating 3.3 h
View Scheme
参考文献
Loader, Charles E.; Barnett, Graham H.; Anderson, Hugh J.
Canadian Journal of Chemistry, 1982 , vol. 60, p. 383 - 389
反应条件
1: 77 percent / phosphorus oxychloride / 1.83 h / 0 °C
2: 67 percent / p-toluenesulfonic acid / H2O; ethanol / 1.) reflux 1 h, 2.) heating 3.3 h
View Scheme
参考文献
Loader, Charles E.; Barnett, Graham H.; Anderson, Hugh J.
Canadian Journal of Chemistry, 1982 , vol. 60, p. 383 - 389
