3-溴-5-乙氧基-4-甲氧基苯甲醛合成路线 （共 3 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide 1 h;
参考文献
Jacob, Peyton; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 7 p. 881 - 888
反应条件
N-bromosuccinmide T=0°C; Solid phase reaction; bromination; 0.0333333 h;
参考文献
Sarma, Jagarlapudi A.R.P.; Nagaraju, Akula; Majumdar, Kanak K.; Samuel, Purnima M.; Das, Indira; Roy, Sujit; McGhie, Alistair J.
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 6 p. 1119 - 1123
反应条件
1: 82 percent / Heating
2: 1.) BuLi / 1.) ether, hexane, -80 deg C, 15 min, 2.) ether, hexane, from -80 deg C to RT
3: aq. HCl / 2 h / 100 °C
4: 43 percent / ammonium acetate / 1 h / Heating
5: AlH3 / tetrahydrofuran / 0.5 h / Heating
View Scheme
参考文献
Jacob, Peyton; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 7 p. 881 - 888
