1-(3,4-二氢苯并吡喃-2-基甲基)-4-苯基-哌嗪合成路线 (共 5 条)
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
6 h; Heating;
参考文献
Pratap, Ram; Gupta, R. C.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1063 - 1067
反应条件
1: 75 percent / hydrogene / Pd/C / acetic acid / 70 °C
2: thionyl chloride / CHCl3 / 3 h / Heating
3: 90 percent / triethylamine / benzene / 24 h
4: 50 percent / LAH / tetrahydrofuran / 6 h / Heating
View Scheme
参考文献
Pratap, Ram; Gupta, R. C.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1063 - 1067
反应条件
1: 90 percent / triethylamine / benzene / 24 h
2: 50 percent / LAH / tetrahydrofuran / 6 h / Heating
View Scheme
参考文献
Pratap, Ram; Gupta, R. C.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1063 - 1067
反应条件
1: 90 percent / triethylamine / benzene / 24 h
2: 50 percent / LAH / tetrahydrofuran / 6 h / Heating
View Scheme
参考文献
Pratap, Ram; Gupta, R. C.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1063 - 1067
反应条件
1: thionyl chloride / CHCl3 / 3 h / Heating
2: 90 percent / triethylamine / benzene / 24 h
3: 50 percent / LAH / tetrahydrofuran / 6 h / Heating
View Scheme
参考文献
Pratap, Ram; Gupta, R. C.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1063 - 1067