4-甲基-6-苯基-3-哒嗪胺合成路线 （共 4 条）
反应条件
potassium hydroxide; nickel monoaluminide in methanol
2 h; Ambient temperature;
参考文献
Sitamze; Schmitt; Wermuth
Journal of Organic Chemistry, 1992 , vol. 57, # 11 p. 3257 - 3258
反应条件
sodium amide in xylene
48 h; Heating;
参考文献
Moustafa, A. H.; Kaddah, A. M.; Shams, N. A.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1084 - 1086
反应条件
1: phosphorus oxychloride / 4 h / 85 - 95 °C
2: hydrazine hydrate / butan-1-ol / 6 h / 100 °C
3: H2 / Raney Ni / methanol / 20 °C / 760 Torr
View Scheme
参考文献
Wermuth, Camille-Georges; Bourguignon, Jean-Jacques; Schlewer, Gilbert; Gies, Jean-Pierre; Schoenfelder, Angele; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 239 - 249
参考文献
American Cyanamid Company
Patent: US4623376 A1, 1986 ;
