6-氯-3-甲基-1-苯基-1H-吡唑并[3,4-b]吡啶-5-甲醛合成路线 (共 2 条)
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate
T=0 - 5°C; Vilsmeier-Hack reaction; 1 h;
2: 1-phenyl-3-methyl-5-acetylaminopyrazole T=80°C; 2 h; Further stages.;
参考文献
El-Emary, Talaat I.
Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 507 - 518
反应条件
trichlorophosphate
1) 90-95 deg C, 3 h, 2) 90-95 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Simay, A.; Takacs, K.; Toth, L.
Acta Chimica Academiae Scientiarum Hungaricae, 1982 , vol. 109, # 2 p. 175 - 188