1: With triethylamine in 1,2-dichloro-ethane
0.0166667 h;
2: With titanium tetrachloride in dichloromethane; 1,2-dichloro-ethane
T=20°C;
3: With water; sodium cyanoborohydride; sodium hydrogencarbonate
more than 3 stages;
参考文献
NOVARTIS AG
Patent: WO2008/63912 A1, 2008 ;
Location in patent: Page/Page column 73 ;