4-甲基-2-(4-甲基-2-吡啶基)吡啶1-氧化物合成路线 （共 5 条）
反应条件
1: 1.) acetic anhydride, 2.) 10percent aq. NaOH / 1.) 60-65 deg C, 24 h, 2.) aq. EtOH, reflux, 30 min 2: 58 percent / MnO2 / CH2Cl2 / Ambient temperature; overnight View Scheme
参考文献
Ciana, Leopoldo Della; Hamachi, Itaru; Meyer, Thomas J.
Journal of Organic Chemistry, 1989 , vol. 54, # 7 p. 1731 - 1735
反应条件
1: With acetic anhydride T=65°C; 17 h; 2: With sodium hydroxide in ethanol; water 0.5 h; Reflux;
参考文献
Kodama, Koichi; Kobayashi, Akinori; Hirose, Takuji
Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5514 - 5517
反应条件
sodium hydroxide; acetic anhydride 1.) 60-65 deg C, 24 h, 2.) aq. EtOH, reflux, 30 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ciana, Leopoldo Della; Hamachi, Itaru; Meyer, Thomas J.
Journal of Organic Chemistry, 1989 , vol. 54, # 7 p. 1731 - 1735
反应条件
1.1: acetic anhydride / 17 h / 65 °C 1.2: 0.5 h / |Reflux 2.1: sulfuric acid; hydrogen bromide / water / 40 h / |Reflux View Scheme
参考文献
Kodama, Koichi; Kobayashi, Akinori; Hirose, Takuji
Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5514 - 5517
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform
48 h; Ambient temperature;
参考文献
Ciana, Leopoldo Della; Hamachi, Itaru; Meyer, Thomas J.
Journal of Organic Chemistry, 1989 , vol. 54, # 7 p. 1731 - 1735
