4-(溴甲基)-4-甲基-2,2-联吡啶合成路线 （共 8 条）
反应条件
sulfuric acid; hydrogen bromide Heating;
参考文献
Berg, Katja E.; Tran, Anh; Raymond, Mary Katherine; Abrahamsson, Malin; Wolny, Juliusz; Redon, Sophie; Andersson, Mikael; Sun, Licheng; Styring, Stenbjoern; Hammarstroem, Leif; Toftlund, Hans; Akermark, Bjoern
European Journal of Inorganic Chemistry, 2001 , # 4 p. 1019 - 1029
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane 3 h; Heating;
参考文献
Hirata, Narukuni; Lagref, Jean-Jacques; Palomares, Emilio J.; Durrant, James R.; Nazeeruddin, M. Khaja; Gratzel, Michael; Di Censo, Davide
Chemistry - A European Journal, 2004 , vol. 10, # 3 p. 595 - 602
反应条件
1,2-dibromo-1,1,2,2-tetrafluoroethane; cesium fluoride in N,N-dimethyl-formamide T=20°C; 3 h;
参考文献
Serin, Jason; Schultze, Xavier; Adronov, Alex; Frechet, Jean M.J.
Macromolecules, 2002 , vol. 35, # 14 p. 5396 - 5404
反应条件
1: 1.2 g / NaBH4; aq. NaOH / methanol / 1 h / 20 °C 2: 98 percent / aq. HBr; H2SO4 / Heating View Scheme
参考文献
European Journal of Inorganic Chemistry, , # 4 p. 1019 - 1029
反应条件
1.1: acetic anhydride / 17 h / 65 °C 1.2: 0.5 h / |Reflux 2.1: sulfuric acid; hydrogen bromide / water / 40 h / |Reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 54, # 40 p. 5514 - 5517
反应条件
sodium hydride in N,N-dimethyl-formamide
T=80°C; 0.5 h; Yield given;
参考文献
Strekowski, Lucjan; Mokrosz, Jerzy L.; Tanious, Farial A.; Watson, Rebecca A.; Harden, Donald; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 6 p. 1231 - 1240
反应条件
lithium diisopropyl amide
1) THF, 0 deg C, 1.5h, 2) THF, RT, 1h; Yield given. Multistep reaction;
参考文献
Furue, Masaoki; Yoshidzumi, Toshiyuki; Kinoshita, Shuichi; Kushida, Takashi; Nozakura, Shun-ichi; Kamachi, Mikiharu
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 5 p. 1632 - 1640
反应条件
Ambient temperature;
参考文献
Furue, Masaoki; Kuroda, Noritaka; Nozakura, Shun-ichi
Chemistry Letters, 1986 , p. 1209 - 1212
