ruthenium trichloride; sodium periodate in water; ethyl acetate; acetonitrile T=20°C; 4 h;

1.1: LDA / tetrahydrofuran / 1 h / -65 - -60 °C 1.2: 44 percent / 1,3-dimethylimidazolidin-2-one / tetrahydrofuran / 4 h / -65 °C 2.1: 88 percent / AlCl3 / 1,2-dichloro-ethane / 5 h / 15 - 25 °C 3.1: 73 percent / NaIO4; RuCl3*H2O / acetonitrile; ethyl acetate; H2O / 4 h / 20 °C View Scheme

1: 88 percent / AlCl3 / 1,2-dichloro-ethane / 5 h / 15 - 25 °C 2: 73 percent / NaIO4; RuCl3*H2O / acetonitrile; ethyl acetate; H2O / 4 h / 20 °C View Scheme

in tetrahydrofuran; diethyl ether T=0 - 20°C;

1: 100 percent / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 93 percent / Lawesson reagent / toluene / 0.5 h / 130 °C View Scheme