2-氯-4-(三氟甲基)苯甲醛合成路线 （共 2 条）
反应条件
1: With diisobutylaluminium hydride in toluene
T=-78°C; Inert atmosphere;
2: With acetic acid in water; toluene
T=0°C; 2 h;
参考文献
ARRAY BIOPHARMA INC.
Patent: WO2009/158426 A1, 2009 ;
Location in patent: Page/Page column 139 ;
WO 2009/158426 A1
反应条件
sec.-butyllithium in tetrahydrofuran
T=-78 - 25°C; 1.5 h;
参考文献
KALYPSYS, INC.
Patent: WO2009/117421 A2, 2009 ;
Location in patent: Page/Page column 139-140 ;
WO 2009/117421 A2
