2-溴-4,6-二苯基-3-氰基吡啶合成路线 （共 16 条）
反应条件
phosphoric acid; pyridin-2-yl hydrobromide; phosphorus oxytribromide in 1,4-dioxane 48 h; Heating;
参考文献
Victory, Pedro; Borrell, Jose I.; Cirujeda, Joan; Vidal-Ferran, Anton
Heterocycles, 1993 , vol. 36, # 4 p. 777 - 783
反应条件
bromine in chloroform T=20°C; 2 h;
参考文献
Krauze, A. A.; Bomika, Z. A.; Pelcher, Yu. E.; Mazheika, I. B.; Dubur, G. Ya.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 4 p. 385 - 390
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 4 p. 508 - 512
反应条件
chloroform; hydrogen bromide
参考文献
Journal of the American Chemical Society, , vol. 44, p. 2909
反应条件
in acetic acid 2 h; Heating;
参考文献
Shestopalov, A. M.; Promonenkov, V. K.; Sharanin, Yu. A.; Rodinovskaya, L. A.; Sharanin, S. Yu.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 7 p. 1382 - 1401
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 7 p. 1517 - 1538
反应条件
1: 50 percent / Br2 / CHCl3 / 20 h / 0 °C 2: 37 percent / Br2 / CHCl3 / 2 h / 20 °C View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 18, # 4 p. 385 - 390
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 18, # 4 p. 508 - 512
反应条件
1: 42 percent / PS5 / toluene / 3 h / Heating 2: 50 percent / Br2 / CHCl3 / 20 h / 0 °C 3: 37 percent / Br2 / CHCl3 / 2 h / 20 °C View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 18, # 4 p. 385 - 390
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 18, # 4 p. 508 - 512
反应条件
1: 55 percent / conc. H2SO4 / 1 h / 100 °C 2: 42 percent / PS5 / toluene / 3 h / Heating 3: 50 percent / Br2 / CHCl3 / 20 h / 0 °C 4: 37 percent / Br2 / CHCl3 / 2 h / 20 °C View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 18, # 4 p. 385 - 390
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 18, # 4 p. 508 - 512
反应条件
1: 13 percent / thiourea / 0.17 h / 200 °C 2: 55 percent / conc. H2SO4 / 1 h / 100 °C 3: 42 percent / PS5 / toluene / 3 h / Heating 4: 50 percent / Br2 / CHCl3 / 20 h / 0 °C 5: 37 percent / Br2 / CHCl3 / 2 h / 20 °C View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 18, # 4 p. 385 - 390
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 18, # 4 p. 508 - 512
反应条件
1: 2.3 g / dimethylformamide / 4 h / Heating
2: 30 percent / 10percent aq. KOH / dimethylformamide / 0.5 h / 15 - 20 °C
View Scheme
参考文献
Krauze, A. A.; Bomika, Z. A.; Shestopalov, A. M.; Rodinovskaya, L. A.; Pelcher, Yu. E'; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 3 p. 279 - 284
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 3 p. 377 - 382
反应条件
1: 2.3 g / dimethylformamide / 4 h / Heating
2: 73 percent / 8.5percent sol. of CH3ONa / methanol / 1 h / Heating
View Scheme
参考文献
Krauze, A. A.; Bomika, Z. A.; Shestopalov, A. M.; Rodinovskaya, L. A.; Pelcher, Yu. E'; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 3 p. 279 - 284
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 3 p. 377 - 382
