1H-imidazole; iodine; triphenylphosphine in dichloromethane T=0 - 20°C;

1: tetrahydrofuran With 1,1-Diiodoethane; Sm2Co7 Substitution; 120 h; Heating; 2: pivaloyl chloride T=25°C; Substitution; 0.25 h;

sodium iodide in acetone 2 h; Ambient temperature;

1: 2.357 g / DMAP, NEt3 / CH2Cl2 / 1.) 0 deg C, 20 min, 2.) RT, 24 h 2: 4.98 g / NEt3, DMAP / CH2Cl2 / 20 h / Ambient temperature 3: 3.120 g / NaI / acetone / 2 h / Ambient temperature View Scheme