1-(三异丙基硅基)-1-丙炔合成路线 （共 14 条）
反应条件
zinc in tetrahydrofuran T=20°C; Dimerization; sonication for 30 min;
参考文献
Lan; Hammond
Journal of Organic Chemistry, 2000 , vol. 65, # 13 p. 4217 - 4221
反应条件
in diethyl ether T=-40 - 0°C;
参考文献
Corey, E. J.; Ruecker, Cristoph
Tetrahedron Letters, 1982 , vol. 23, # 7 p. 719 - 722
反应条件
t-Bu-XantPhos; dichloro bis(acetonitrile) palladium(II); potassium carbonate; cesium fluoride in toluene T=100°C; 20 h; Inert atmosphere;
参考文献
Liu, Yan-Yun; Yang, Xu-Heng; Huang, Xiao-Cheng; Wei, Wen-Ting; Song, Ren-Jie; Li, Jin-Heng
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10421 - 10426
反应条件
1: 79 percent / n-BuLi / tetrahydrofuran; hexane / 1.) -78 deg C, 10 min; -78 to -20 deg C, 2.) -78 deg C, 20 min; 0 deg C, 5 h 2: 80 percent / ethanol / 9 h / 80 °C 3: 77 percent / pyridine / diethyl ether 4: Pd(PPh3)4 / toluene / 24 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 14 p. 4650 - 4652
反应条件
1: 77 percent / pyridine / diethyl ether 2: Pd(PPh3)4 / toluene / 24 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 14 p. 4650 - 4652
反应条件
1: 80 percent / ethanol / 9 h / 80 °C 2: 77 percent / pyridine / diethyl ether 3: Pd(PPh3)4 / toluene / 24 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 14 p. 4650 - 4652
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene 24 h; Heating; Yields of byproduct given;
参考文献
Ogoshi, Sensuke; Nishiguchi, Shinji; Tsutsumi, Ken; Kurosawa, Hideo
Journal of Organic Chemistry, 1995 , vol. 60, # 14 p. 4650 - 4652
反应条件
ethylmagnesium bromide 1.) THF, -78 deg C, 2.) THF, reflux, 24 h; Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 111, # 13 p. 4873 - 4878
反应条件
1: 64 percent / n-BuLi / tetrahydrofuran; hexane / 1 h / 0 °C 2: Zn / tetrahydrofuran / 20 °C / sonication for 30 min View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 13 p. 4217 - 4221
反应条件
1: tris(1-methylethyl)(prop-1-yn-1-yl)silane With n-butyllithium in tetrahydrofuran; hexane T=-78°C; Metallation; 2.5 h; 2: 2-(Bromomethyl)-1-iodonaphthalene in tetrahydrofuran; hexane T=-78°C; Substitution; 2.5 h;
参考文献
Stara, Irena G.; Kollarovic, Adrian; Teply, Filip; Stary, Ivo; Saman, David; Fiedler, Pavel
Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 4 p. 577 - 609
