反应条件
1: 57 percent / diethyl azodicarboxylate, PPh3 / tetrahydrofuran / 0.25 h / Ambient temperature; reactions of cyclohex-2-enol with diacylamines under Mitsunobu reaction conditions, stereocontrolled preparation of cyclohexane amino alcohols 2: 96 percent / NBS / CHCl3; ethanol / 8 h / Ambient temperature 3: 98 percent / 2 M HCl / methanol / 0.5 h / Ambient temperature 4: 80 percent / tributyltin hydride, AIBN / toluene; methanol / 1 h / Heating 5: 1.) hydrazine hydrate, 2.) conc. HCl / 1.) 95 percent ethanol, reflux, 2 h, 2.) room temperature View Scheme
参考文献
Sammes, Peter G.; Thetford, Dean
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 655 - 661
