2-(羟基亚甲基)环己酮合成路线 (共 42 条)
反应条件
1: NaOAc / methanol; H2O 2: CH3COOH; HCl / H2O View Scheme
参考文献
Joseph, Delphine; Martarello, Laurent; Kirsch, Gilbert
Journal of Chemical Research, Miniprint, 1995 , # 9 p. 2001 - 2014
反应条件
acidic medium according to lit. cit. 2, 8; Multistep reaction;
参考文献
Chakraborty, Suchandra; Chattopadhyay, Gautam; Saha, Chandan
Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 2 p. 331 - 338
反应条件
hydrogen cation 2.) THF, reflux; Yield given. Multistep reaction;
参考文献
Okada, Keiji; Hosoda, Yasushi; Oda, Masaji
Tetrahedron Letters, 1986 , vol. 27, # 51 p. 6213 - 6216
参考文献
Palmer,M.H.; Scollick,N.M.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 2836 - 2841
反应条件
1: H3PO4 / methanol / 24 h / Ambient temperature 2: LiAlH4 View Scheme
参考文献
Bardou,L. et al.
Bulletin de la Societe Chimique de France, 1967 , p. 297 - 306
反应条件
1: K2CO3 / acetone 2: diethyl ether 3: aq. HCl / methanol View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 44, p. 620 - 627
参考文献
Dreiding; Nickel
Journal of the American Chemical Society, 1954 , vol. 76, p. 3965,3967
反应条件
potassium carbonate in dimethyl sulfoxide T=50°C; 12 h; Yield given. Yields of byproduct given;
参考文献
Marvell, Elliot N.; Hilton, Charles; Cleary, Michael
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4272 - 4275
反应条件
toluene-4-sulfonic acid in benzene 4 h; Heating;
参考文献
Eberbach; Laber
Tetrahedron Letters, 1992 , vol. 33, # 1 p. 57 - 60
反应条件
potassium carbonate in acetone 26 h; Heating;
参考文献
Jacquier,R. et al.
Bulletin de la Societe Chimique de France, 1970 , p. 2678 - 2685