BOC-D-3-三氟甲基苯丙氨酸合成路线 （共 6 条）
反应条件
sodium hydroxide; magnesium oxide in 1,4-dioxane T=25°C;
参考文献
Nestor Jr.; Ho; Simpson; Horner; Jones; McRae; Vickery
Journal of Medicinal Chemistry, 1982 , vol. 25, # 7 p. 795 - 801
反应条件
1: 86 percent / BF3*OEt2 / 1 h / Heating 3: 95 percent / 6N aq. HCl / 2 h / Heating 4: 91 percent / 1N aq. NaOH, MgO / dioxane / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 25, # 7 p. 795 - 801
反应条件
1: NaOH 2: 86 percent / BF3*OEt2 / 1 h / Heating 4: 95 percent / 6N aq. HCl / 2 h / Heating 5: 91 percent / 1N aq. NaOH, MgO / dioxane / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 25, # 7 p. 795 - 801
反应条件
2: 95 percent / 6N aq. HCl / 2 h / Heating 3: 91 percent / 1N aq. NaOH, MgO / dioxane / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 25, # 7 p. 795 - 801
反应条件
1: 95 percent / 6N aq. HCl / 2 h / Heating 2: 91 percent / 1N aq. NaOH, MgO / dioxane / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 25, # 7 p. 795 - 801
反应条件
1: Et3N / tetrahydrofuran 2: diethyl ether 3: aq. C6H5CO2Ag / dioxane / 20 °C / sonication View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 18 p. 4759 - 4762
