3-溴-5-氯-2-(三氟甲基)吡啶合成路线 （共 3 条）
反应条件
1-methyl-pyrrolidin-2-one; potassium fluoride; copper(l) iodide
Heating;
参考文献
Cottet, Fabrice; Schlosser, Manfred
Tetrahedron, 2004 , vol. 60, # 51 p. 11869 - 11874
反应条件
1: hydrobromic acid; bromine; sodium nitrite / H2O / -5 - 60 °C
2: 9.7 g / sodium iodide; chlorotrimethylsilane / various solvent(s) / 0.75 h / Heating
3: 69 percent / potassium fluoride; cuprous iodide; N-methylpyrrolidinone / Heating
View Scheme
参考文献
Cottet, Fabrice; Schlosser, Manfred
Tetrahedron, 2004 , vol. 60, # 51 p. 11869 - 11874
反应条件
1: 9.7 g / sodium iodide; chlorotrimethylsilane / various solvent(s) / 0.75 h / Heating
2: 69 percent / potassium fluoride; cuprous iodide; N-methylpyrrolidinone / Heating
View Scheme
参考文献
Cottet, Fabrice; Schlosser, Manfred
Tetrahedron, 2004 , vol. 60, # 51 p. 11869 - 11874
