1-(3-甲基-4-吡啶基)乙酮合成路线 （共 4 条）
反应条件
1: in tetrahydrofuran; hexane
T=0°C;
2: With ammonium chloride in tetrahydrofuran; hexane; water
Saturated solution;
参考文献
Hay, Michael P.; Turcotte, Sandra; Flanagan, Jack U.; Bonnet, Muriel; Chan, Denise A.; Sutphin, Patrick D.; Nguyen, Phuong; Giaccia, Amato J.; Denny, William A.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 2 p. 787 - 797
参考文献
DOV PHARMACEUTICAL, INC.
Patent: WO2005/84439 A1, 2005 ;
Location in patent: Page/Page column 44 ;
WO 2005/084439 A1
反应条件
in tetrahydrofuran; diethyl ether
14 h; Ambient temperature;
参考文献
Hibino; Sugino
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1751 - 1755
反应条件
1: 1.) (CH3)2SO4 / 1.) 14 h, r.t., 2.) 50percent aq. EtOH, 14 h, r.t.
2: 71 percent / diethyl ether; tetrahydrofuran / 14 h / Ambient temperature
View Scheme
参考文献
Hibino; Sugino
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1751 - 1755
