2-氯-5-三氟甲基苯甲醛合成路线 （共 6 条）
反应条件
2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; copper diacetate in water; acetonitrile T=20°C; 6 h; Green chemistry;
参考文献
Tetrahedron Letters, , vol. 55, # 10 p. 1677 - 1681
反应条件
hydrogenchloride; (CH2)6N4 1) 2 h reflux in AcOH-H2O; 2) 15 min. reflux; Yield given. Multistep reaction;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 3 p. 967 - 983
反应条件
hydrogenchloride; sodium acetate; copper(II) sulfate; sodium sulfite; sodium nitrite 1) H2O, 0-5 deg C; 2) 2 h, 10-20 deg C; 3) aq. HCl; Yield given. Multistep reaction;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 3 p. 967 - 983
反应条件
1: 99 percent / NaBH4 / dioxane; H2O / 0.5 h / 30 - 40 °C 2: 86 percent / SOCl2 / CHCl3; pyridine / 48 h / 10 - 20 °C View Scheme
参考文献
Sindelar; Holubek; Ryska; et al.
Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 3 p. 967 - 983
反应条件
sodium tetrahydroborate in 1,4-dioxane; water T=30 - 40°C; 0.5 h;
参考文献
Sindelar; Holubek; Ryska; et al.
Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 3 p. 967 - 983
反应条件
1: 97 percent / NaOH / hexamethylphosphoric acid triamide / 6 h / 100 °C 2: 1) Mg / 1) THF, 2) THF, reflux, 4 h 3: 0.23 g / NaH / dimethylformamide / 16 h / 70 °C View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 11 p. 3077 - 3093
