反应条件
1.1: n-butyllithium; N,N,N',N,-tetramethylethylenediamine / hexane / 1.25 h / Inert atmosphere; Cooling with ice 1.2: 1 h / 20 °C / Cooling with ice 2.1: n-butyllithium; N,N,N',N,-tetramethylethylenediamine / hexane / 1.25 h / Inert atmosphere; Cooling with ice 2.2: 1 h / 20 °C / Cooling with ice 3.1: hydrogenchloride; water / methanol / 4 h / 90 °C 4.1: bromine; acetic acid / 0.33 h / 20 °C / Cooling with ice 5.1: N,N-dimethyl-formamide / 5 h / 154 °C 6.1: sodium hydride / 1,4-dioxane / 0.03 h / 20 °C 6.2: 0.17 h / 20 °C 6.3: 6 h / 155 °C 7.1: ammonia / 1,4-dioxane / 24 h / 150 °C View Scheme
参考文献
Wang, Wei; Wu, Wenchao; Shen, Zucheng; Chen, Liqin
Journal of Labelled Compounds and Radiopharmaceuticals, 2011 , vol. 54, # 7 p. 371 - 373
