反应条件
1: 74 percent / 1.) sodium hydride / 1.) mineral oil, THF, r.t., 30 min; 2.) THF, 4 h, reflux
2: 95 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
3: 96 percent / 2,6-di-tert-butyl-p-cresole, Lipase PS / diisopropyl ether; H2O / 1.5 h / Ambient temperature
4: 91 percent / 4-dimethylaminopyridine, pyridine / CH2Cl2 / 15 h / Ambient temperature
5: 93 percent / guanidine / ethanol / 1 h / Ambient temperature
6: 99 percent / pyridine / CH2Cl2 / 40 h / Ambient temperature
7: 88 percent / dimethylsulfoxide / 24 h / 90 °C
8: 1.) aq. 2M-NaOH; 2.) aq. 2M-NaOH / 1.) ETOH, r.t., 18 h; 2.) 3h reflux
View Scheme
参考文献
Shiotani, Shunsaku; Okada, Hirohiko; Yaroamoto, Takako; Nakamata, Kumiko; Adachi, Jun; Nakamoto, Hiromasa
Heterocycles, 1996 , vol. 43, # 1 p. 113 - 126
