2-(4-羟基苯基)-1-苯基-合成路线 （共 6 条）
反应条件
hydrogen bromide; acetic acid 4 h; Heating;
参考文献
Ruenitz, Peter C.; Bagley, Jerome R.; Mokler, Corwin M.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1056 - 1060
反应条件
1: 1.) NaH / 1.) DMF, 2.) DMF 2: 82 percent / 48percent aq. HBr, acetic acid / 4 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 25, # 9 p. 1056 - 1060
反应条件
1-ethyl-piperidine; tin(II) trifluoromethanesulfonate; chloro-trimethyl-silane 1)CH2Cl2, -78 deg C, 40 min, 2) CH2Cl2, -78 deg C, 30 min, 3) CH2Cl2, -78 deg C; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 43, # 21 p. 5003 - 5018
反应条件
1: 98percent H2SO4 / 12 h / Ambient temperature 2: 1.) C2H5MgBr, 3.) HCl View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 25, # 9 p. 1056 - 1060
反应条件
1: 98percent H2SO4 / 12 h / Ambient temperature
2: 1.) C2H5MgBr, 3.) HCl
View Scheme
参考文献
Ruenitz, Peter C.; Bagley, Jerome R.; Mokler, Corwin M.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1056 - 1060
反应条件
sulfuric acid
12 h; Ambient temperature;
参考文献
Ruenitz, Peter C.; Bagley, Jerome R.; Mokler, Corwin M.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1056 - 1060
