4-[2-(三氟甲基)苯氧基]哌啶合成路线 (共 2 条)
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 24 h;
参考文献
PIERRE FABRE MEDICAMENT; Leroy, Isabelle; Dupont-Passelaigue, Elisabeth; Mialhe, Samuel; Junquero, Didier; Valeille, Karine
Patent: US2013/40928 A1, 2013 ;
Location in patent: Paragraph 0212; 0213 ;
反应条件
1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 25 h / 0 - 70 °C 2: trifluoroacetic acid / dichloromethane / 24 h / 20 °C View Scheme