in tetrahydrofuran; diethyl ether T=20°C; Grignard addition; 12 h;

1: With dimethylsulfide borane complex in tetrahydrofuran T=20°C; 12 h; 2: With sodium hydroxide; ethanol; dihydrogen peroxide in tetrahydrofuran T=20°C; 2 h; 3: With di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran T=0 - 20°C; Mitsunobu reaction;