4-乙基-N,N-二苯基-1-萘甲酰胺合成路线 (共 3 条)
反应条件
potassium hydroxide in diethylene glycol 8 h; Heating;
参考文献
Martin, Billy R.; Huffman, John W.
Patent: US2005/9903 A1, 2005 ;
Location in patent: Page 23 ;
US 20050009903 A1
反应条件
aluminium trichloride in 1,2-dichloro-ethane
Friedel-Crafts reaction; 6 h; Heating;
参考文献
Martin, Billy R.; Huffman, John W.
Patent: US2005/9903 A1, 2005 ;
Location in patent: Page 23 ;
US 20050009903 A1
反应条件
1: 90 percent / KOH / bis-(2-hydroxy-ethyl) ether / 8 h / Heating
2: thionyl chloride / 0.25 h / Heating
View Scheme
参考文献
Huffman, John W.; Zengin, Gulay; Wu, Ming-Jung; Lu, Jianzhong; Hynd, George; Bushell, Kristen; Thompson, Alicia L.S.; Bushell, Simon; Tartal, Cindy; Hurst, Dow P.; Reggio, Patricia H.; Selley, Dana E.; Cassidy, Michael P.; Wiley, Jenny L.; Martin, Billy R.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 1 p. 89 - 112