6-溴-1,3-苯并二氧戊环-5-甲酰胺合成路线 （共 7 条）
反应条件
ammonium hydroxide
T=0 - 20°C; 2 h;
参考文献
Praveen, Chandrasekaran; Dheenkumar; Perumal
Journal of Chemical Sciences, 2013 , vol. 125, # 1 p. 71 - 83
反应条件
1: Oxonereg; / N,N-dimethyl-formamide / 1 h / 20 °C
2: thionyl chloride / diethyl ether / 1 h / 0 - 5 °C
3: ammonium hydroxide / 2 h / 0 - 20 °C
View Scheme
参考文献
Praveen, Chandrasekaran; Dheenkumar; Perumal
Journal of Chemical Sciences, 2013 , vol. 125, # 1 p. 71 - 83
反应条件
1: thionyl chloride / diethyl ether / 1 h / 0 - 5 °C
2: ammonium hydroxide / 2 h / 0 - 20 °C
View Scheme
参考文献
Praveen, Chandrasekaran; Dheenkumar; Perumal
Journal of Chemical Sciences, 2013 , vol. 125, # 1 p. 71 - 83
反应条件
bromine in chloroform; water
参考文献
Beugelmans, Rene; Ginsburg, Helene; Bois-Choussy, Michele
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1149 - 1152
反应条件
1: NH4OH, 2,4,6-trichloro-s-triazine
2: Br2 / CHCl3; H2O
View Scheme
参考文献
Beugelmans, Rene; Ginsburg, Helene; Bois-Choussy, Michele
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1149 - 1152
反应条件
N-bromosuccinmide; chloroform
Behandeln der Reaktionsloesung mit Ammoniak;
参考文献
Yamaguchi
Nippon Kagaku Kaishi, 1956 , vol. 77, p. 591,592
Chem.Abstr., 1958 , p. 305
反应条件
piperidine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide
1.4 h; Heatingor Et3N instead of azacyclohexane;
参考文献
Grotjahn; Vollhardt
Synthesis, 1993 , # 6 p. 579 - 605
