1: 85 percent / dimethylformamide / 22 h / 65 °C 2: 100 percent / aluminum hydride / tetrahydrofuran / 2.5 h / 0 °C 3: 90 percent / CBr4, ethylenebis(diphenylphosphine) / CH2Cl2 / 2.5 h / -35 °C 4: 153 mg / acetonitrile / 1.5 h / 20 °C 5: 1.) n-BuLi, 2.) HMPA / 1.) THF, hexane, -100 deg C, 2 min, 2.) THF, hexane, from -100 deg C to RT 6: 61 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 15 h / Ambient temperature 7: potassium carbonate / methanol; H2O / 7.5 h / Ambient temperature 8: AcOH / H2O View Scheme