1: With hydrogen bromide in water; acetonitrile T=0°C; 0.166667 h; 2: With sodium nitrite in water; acetonitrile T=0°C; 1.08333 h; 3: With copper(I) bromide in water; acetonitrile T=70°C; 1.5 h;
参考文献
Kawahara, Eiji; Miyake, Takahiro; Roesel, Johannes
Patent: US2008/293708 A1, 2008 ;
Location in patent: Page/Page column 37 ;
1: 1) 48percent HBr, NaNO2 2) CuBr / 1) water, 1 h, 0 deg C 2) a) 30 min, r.t. b) 90 min, 70 deg C 2: SOCl2 / CH2Cl2 / 1 h / Heating 3: NH3-gas / CH2Cl2 / 1 h 4: 79 percent / Br2, NaOH / 1) 4 h, 0 deg C 2) 3 h, 60 deg C View Scheme
参考文献
McKittrick, Brian; Failli, Amedeo; Steffan, Robert J.; Soll, Richard M.; Hughes, Philip; et al.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 2151 - 2163
1: 1) 48percent HBr, NaNO2 2) CuBr / 1) water, 1 h, 0 deg C 2) a) 30 min, r.t. b) 90 min, 70 deg C 2: SOCl2 / CH2Cl2 / 1 h / Heating 3: NH3-gas / CH2Cl2 / 1 h View Scheme
参考文献
McKittrick, Brian; Failli, Amedeo; Steffan, Robert J.; Soll, Richard M.; Hughes, Philip; et al.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 2151 - 2163
