(3b,5b,15a,16a)-15,16-二氢-3,5-二羟基-3’H-环丙并[15,16]雄甾-6,15-二烯-17-酮合成路线 （共 13 条）
反应条件
copper; zinc in ethylene glycol dimethyl ether T=55°C; 5 h;
参考文献
Bittler, Dieter; Hofmeister, Helmut; Laurent, Henry; Nickisch, Klaus; Petzoldt, Karl; et al.
Angewandte Chemie, 1982 , vol. 94, # 9 p. 718 - 719
反应条件
1: 88 percent / Zn/Cu / 1,2-dimethoxy-ethane / 5 h / 55 °C
2: 69 percent / KOEt / tetrahydrofuran / 2 h / Ambient temperature
3: 95 percent / H2 / Pd/CaCO3 / tetrahydrofuran; propan-2-ol / 2 h / 750.06 Torr / Ambient temperature
4: 62 percent / pyridinium dichromate / dimethylformamide / 24 h / 70 °C
5: 59 percent / DDQ / dioxane / 1.5 h / 100 °C
View Scheme
参考文献
Bittler, Dieter; Hofmeister, Helmut; Laurent, Henry; Nickisch, Klaus; Petzoldt, Karl; et al.
Angewandte Chemie, 1982 , vol. 94, # 9 p. 718 - 719
反应条件
1: 88 percent / Zn/Cu / 1,2-dimethoxy-ethane / 5 h / 55 °C
2: 69 percent / KOEt / tetrahydrofuran / 2 h / Ambient temperature
View Scheme
参考文献
Bittler, Dieter; Hofmeister, Helmut; Laurent, Henry; Nickisch, Klaus; Petzoldt, Karl; et al.
Angewandte Chemie, 1982 , vol. 94, # 9 p. 718 - 719
