5-碘哒嗪-3(2H)-酮合成路线 (共 3 条)
反应条件
hydrogen iodide in water T=150°C; 25 h; Product distribution / selectivity;
参考文献
Becknell, Nadine C.; Lyons, Jacquelyn A.; Aimone, Lisa D.; Huang, Zeqi; Gruner, John A.; Raddatz, Rita; Hudkins, Robert L.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 12 p. 3880 - 3886
反应条件
aluminium trichloride in toluene T=120°C;
参考文献
Coelho, Alberto; Sotelo, Eddy; Novoa, Hector; Peeters, Oswald M.; Blaton, Norbert; Ravina, Enrique
Tetrahedron, 2004 , vol. 60, # 52 p. 12177 - 12189
反应条件
in water
Heating / reflux;
参考文献
Cephalon, Inc.
Patent: US2008/27041 A1, 2008 ;
Location in patent: Page/Page column 78 ;
US 20080027041 A1