1: 2-acetoxy-3-bromo-5-chlorobenzoic acid With triethylamine; isobutyl chloroformate in tetrahydrofuran
T=-15°C; 0.0833333 h;
2: 2-chloro-aniline in tetrahydrofuran
T=20°C; 48 h;
参考文献
Kanamori, Daisuke; Okamura, Taka-Aki; Yamamoto, Hitoshi; Shimizu, Shigeomi; Tsujimoto, Yoshihide; Ueyama, Norikazu
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 11 p. 2057 - 2064
1.1: 92 percent / Et3N / tetrahydrofuran
2.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 0.08 h / -15 °C
2.2: 62 percent / tetrahydrofuran / 48 h / 20 °C
View Scheme
参考文献
Kanamori, Daisuke; Okamura, Taka-Aki; Yamamoto, Hitoshi; Shimizu, Shigeomi; Tsujimoto, Yoshihide; Ueyama, Norikazu
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 11 p. 2057 - 2064
Kanamori, Daisuke; Okamura, Taka-Aki; Yamamoto, Hitoshi; Shimizu, Shigeomi; Tsujimoto, Yoshihide; Ueyama, Norikazu
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 11 p. 2057 - 2064
