2,3,4,6-四-O-(苯基甲基)-D-半乳糖酸 D-内酯合成路线 （共 19 条）
反应条件
4 A molecular sieve; pyridinium chlorochromate in dichloromethane
0.75 h; Ambient temperature;
参考文献
Dondoni; Scherrmann
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6404 - 6412
反应条件
boron trifluoride diethyl etherate; dihydrogen peroxide in diethyl ether; toluene
T=-30°C; Molecular sieve;
参考文献
Szechner, Barbara; Furman, Bartlomiej; Chmielewski, Marek
Carbohydrate Research, 2013 , vol. 369, p. 54 - 57
反应条件
osmium(VIII) oxide; tetrabutylammonium (meta)periodate; 4-methylmorpholine N-oxide in 1,4-dioxane
T=50°C; 120 h;
参考文献
Kitov, Pavel I.; Bundle, David R.
Organic Letters, 2001 , vol. 3, # 18 p. 2835 - 2838
反应条件
pyridine; p-toluenesulfonyl chloride
T=50°C; 20 h;
参考文献
Heightman; Ermert; Klein; Vasella
Helvetica Chimica Acta, 1995 , vol. 78, # 2 p. 514 - 532
反应条件
carbon tetrabromide; triphenylphosphine in acetonitrile
0.333333 h; Ambient temperature;
参考文献
Heightman; Ermert; Klein; Vasella
Helvetica Chimica Acta, 1995 , vol. 78, # 2 p. 514 - 532
反应条件
4 A molecular sieve in toluene
T=130°C; 14 h; closed vial; Yield given;
参考文献
Dondoni, Alessandro; Marra, Alberto
Heterocycles, 1999 , vol. 50, # 1 p. 419 - 426
反应条件
1: With pyridine in dichloromethane
3 h;
2: in dichloromethane
T=20°C; 10 h; Title compound not separated from byproducts;
参考文献
Mangholz, Sissi E.; Briner, Karin; Bernet, Bruno; Vasella, Andrea
Helvetica Chimica Acta, 2003 , vol. 86, # 7 p. 2490 - 2508
反应条件
1: Amberlite IR 120 / 115 °C
2: tetra-(n-butyl)ammonium iodide; sodium hydride / N,N-dimethyl-formamide
3: sulfuric acid; acetic acid / 145 °C
4: acetic anhydride; dimethyl sulfoxide
View Scheme
参考文献
Leaver, David J.; Hughes, Andrew B.; Polyzos, Anastasios; White, Jonathan M.
Journal of Carbohydrate Chemistry, 2010 , vol. 29, # 8-9 p. 379 - 385
反应条件
1: N-iodo-succinimide; water / acetone
2: acetic anhydride; dimethyl sulfoxide / 20 °C
View Scheme
参考文献
Lambu, Mallikharjuna Rao; Hussain, Altaf; Sharma, Deepak K.; Yousuf, Syed Khalid; Singh, Baldev; Tripathi, Anil. K.; Mukherjee, Debaraj
RSC Advances, 2014 , vol. 4, # 22 p. 11023 - 11028
反应条件
1: boron trifluoride diethyl etherate / dichloromethane / 12 h / 0 - 20 °C
2: sodium methylate; methanol
3: sodium hydride / N,N-dimethyl-formamide / 12 h / 0 - 20 °C
4: N-iodo-succinimide; water / acetone
5: acetic anhydride; dimethyl sulfoxide / 20 °C
View Scheme
参考文献
Lambu, Mallikharjuna Rao; Hussain, Altaf; Sharma, Deepak K.; Yousuf, Syed Khalid; Singh, Baldev; Tripathi, Anil. K.; Mukherjee, Debaraj
RSC Advances, 2014 , vol. 4, # 22 p. 11023 - 11028
