(R)-2-(3-(叔丁氧基羰基氨基)-2-氧代哌啶-1-基)乙酸合成路线 （共 3 条）
反应条件
1: 100 percent / H2, AcOH / Pd/C / methanol; H2O / 1810.02 - 2585.7 Torr
2: EDC, HOBt, NMM / acetonitrile / Ambient temperature
3: LiHMDS / tetrahydrofuran / Ambient temperature
4: 100 percent / H2 / Pd/C / ethanol / 1551.4 Torr
View Scheme
参考文献
Semple; Rowley; Brunck; Ha-Uong; Minami; Owens; Tamura; Goldman; Siev; Ardecky; Carpenter; Ge; Richard; Nolan; Hakanson; Tulinsky; Nutt; Ripka
Journal of Medicinal Chemistry, 1996 , vol. 39, # 23 p. 4531 - 4536
反应条件
1: EDC, HOBt, NMM / acetonitrile / Ambient temperature
2: LiHMDS / tetrahydrofuran / Ambient temperature
3: 100 percent / H2 / Pd/C / ethanol / 1551.4 Torr
View Scheme
参考文献
Semple; Rowley; Brunck; Ha-Uong; Minami; Owens; Tamura; Goldman; Siev; Ardecky; Carpenter; Ge; Richard; Nolan; Hakanson; Tulinsky; Nutt; Ripka
Journal of Medicinal Chemistry, 1996 , vol. 39, # 23 p. 4531 - 4536
反应条件
1: LiHMDS / tetrahydrofuran / Ambient temperature
2: 100 percent / H2 / Pd/C / ethanol / 1551.4 Torr
View Scheme
参考文献
Semple; Rowley; Brunck; Ha-Uong; Minami; Owens; Tamura; Goldman; Siev; Ardecky; Carpenter; Ge; Richard; Nolan; Hakanson; Tulinsky; Nutt; Ripka
Journal of Medicinal Chemistry, 1996 , vol. 39, # 23 p. 4531 - 4536
